“Like neutrinos. That’s right! Like neutrinos!” With the recent awarding of the 2015 Nobel Prize in Physics for the demonstration of neutrino transformations and mass, you would not expect these words to belong to a stem cell biologist. But they are exactly what James L. Sherley, founder and director of stem cell biotechnology start-up company
Time to count stem cells to address bluebird bio’s gene therapy problem – Seven years without needing a blood transfusion reads like a one-treatment gene therapy cure for beta thalassemia until a patient suddenly needs one. Gene therapy news this week featured this new problem encountered by gene therapy company bluebird bio, inc. (BLUE: NASDAQ). Bluebird executives
Source of liver stem cells identified “We’ve solved a very old problem,” says Roel Nusse, an HHMI investigator at Stanford University who led the research. Asymmetrex says, “Wait a minute! Hold that phone call for at least a moment, please!” The new evidence for homeostatic stem cells located around central veins in the liver does
Stem Cell Therapy for Pets June 18, 2015 Asymmetrex calls for the scientific method to understand pet “stem cell” therapies. “Once, some farmers thought that shed horsehairs spontaneously generated living worms, until the scientific method uncovered associated Gordian worms as the responsible organisms. In contrast, when extracts of foxglove plants were found to help dropsy
To a full room of attendees for the “Applying 3D Models for Toxicological Research” track of the 14th Annual World Preclinical Congress (WPC) in Boston, Asymmetrex Director James L. Sherley, M.D., Ph.D. explained how giving more attention to tissue stem cell dynamics could bring greater improvements to the physiological relevance of tissue-engineered systems for drug
Fetal stem cells and the sports heroes they revitalized – A SPECIAL REPORT BY USA TODAY SPORTS REVEALS HOW A STEM-CELL MANUFACTURER AVERTED CONTROVERSY IN THE TREATMENTS OF GORDIE HOWE AND JOHN BRODIE. May 22, 2015 – Original Article: Brent Schrotenboer, USA TODAY Sports “In the new business of stem cell medicine, legal and ethical remain
Using stem cells to grow new hair – Researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected by hair
Article Stem Cells by Stuart P. Atkinson “A very exciting demonstration of the remarkable potential of combining gene editing and regenerative medicine. Though future treatment with edited iPSC-derived red blood cells is unlikely to be achieved, the reported experimental systems could reveal the way to safely edit sickle cell patients’ own adult blood stem cells,
First Stem Cell-Based Approach to Treat Type 2 Diabetes – A combination of human stem cell transplantation and anti-diabetic drugs proved to be highly effective at improving body weight and glucose metabolism in a mouse model of type 2 diabetes. Article by ScienceDaily “Heroic study, but modest findings. #WeighTheFood. Some data could be explained by differences
T Memory Stem Cells May Be Key to Gene Therapy – Genetically engineered T memory stem cells (Tscm) can last more than 12 years in patients’ bodies, and can continually generate appropriate T cell armies for them, says an innovative study looking at two historic clinical trials. This exciting demonstration, is a “Super Like” for