What are adult tissue stem cells?

Cells that are a small fraction of total tissue cells (less than 1 per 1000 tissue cells) that maintain the entire genetic program of the tissue without showing it, but are able to continuously divide and produce non-stem sister cells that do execute the genetic program of the tissue.

How are adult tissue stem cells different from embryonic stem cells?

Adult tissue stem cells have the capacity for asymmetric self-renewal, which means they can divide to produce differentiating cells but not differentiate themselves. Embryonic stem cells do not have the capacity of asymmetric self-renewal. In order to produce differentiating cells, they themselves must differentiate, too. Embryonic stem cells also have the problem of high levels of mutation and tumor-formation. Adult tissue stem cells do not. Embryonic stem cells differentiate into immature tissues that are not found in the body after birth. Adult tissue stem cells produce mature differentiated cells like the ones found in the body after birth.

How are adult tissue stem cells different from induced pluripotent stem cells?

Adult tissue stem cells have the capacity for asymmetric self-renewal, which means they can divide to produce differentiating cells but not differentiate themselves. Induced pluripotent stem cells do not have the capacity of asymmetric self-renewal. In order to produce differentiating cells, they themselves must differentiate, too. Induced pluripotent stem cells also have the problem of high levels of mutation and tumor-formation. Adult tissue stem cells do not. Induced pluripotent stem cells differentiate into immature tissues that are not found in the body after birth. Adult tissue stem cells produce mature differentiated cells like the one’s found in the body after birth.

What are the greatest challenges to realizing the promise of regenerative medicine?

Improving and advancing technologies for producing and counting human adult tissue stem cells.

Where were Asymmetrex's technologies developed?

The adult tissue stem cell production and counting technologies were developed in research led by the founder at the Massachusetts Institute of Technology and the now defunct Boston Biomedical Research Institute. The adult tissue stem cell estimation technology was developed with strategic partner AlphaSTAR Corporation.

Does Asymmetrex own its intellectual property?

Adult tissue stem cell production and counting patents are held by Asymmetrex. The adult tissue stem cell estimation intellectual property is held jointly with strategic partner AlphaSTAR Corporation.

Is Asymmetrex intellectual property available for exclusive licensing?

Yes, on a case by case basis limited to specific fields of use.

Does Asymmetrex engage in research and development involving human embryonic stem cells?

No.

Does Asymmetrex accept private donor contributions?

Asymmetrex does not accept non-investment contributions from private donors, unless the purpose is to establish a not-for-profit research division of the company.

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