iPSCs and CRISPR - Daring Duo Fight Sickle Cell Disease

iPSCs and CRISPR – Daring Duo Fight Sickle Cell Disease

Article Stem Cells by Stuart P. Atkinson  “A very exciting demonstration of the remarkable potential of combining gene editing and regenerative medicine.  Though future treatment with edited iPSC-derived red blood cells is unlikely to be achieved, the reported experimental systems could reveal the way to safely edit sickle cell patients’ own adult blood stem cells,

First Stem Cell-Based Approach to Treat Type 2 Diabetes

First Stem Cell-Based Approach to Treat Type 2 Diabetes

First Stem Cell-Based Approach to Treat Type 2 Diabetes – A combination of human stem cell transplantation and anti-diabetic drugs proved to be highly effective at improving body weight and glucose metabolism in a mouse model of type 2 diabetes. Article by ScienceDaily “Heroic study, but modest findings.  #WeighTheFood.  Some data could be explained by differences

T Memory Stem Cells May Be Key to Gene Therapy

T Memory Stem Cells May Be Key to Gene Therapy

T Memory Stem Cells May Be Key to Gene Therapy – Genetically engineered T memory stem cells (Tscm) can last more than 12 years in patients’ bodies, and can continually generate appropriate T cell armies for them, says an innovative study looking at two historic clinical trials. This exciting demonstration, is a “Super Like” for

Immortal Strands | Stem Cell Medicine

Immortal Strands | Stem Cell Medicine

Immortal Strands- Still Alive and Well Another arrow aimed at the heart of Cairns’ immortal strand “hypothesis” is a coming soon attraction in the journal Stem Cell Research.  Such reports are of interest to Asymmetrex, because the company’s most specific adult tissue stem cell biomarkers are based on immortal strands. While other reports that have argued against

Undermining Stem Cell Medicine

Undermining Stem Cell Medicine

Because of the imperfect nature of biomedical research, even outstanding scientists may make problematic recommendations for public science policy.  Preeminent stem cell biologist Dr. Mahendra Rao is promoting cost-effective strategies for establishing public banks of induced pluripotent stem cells (iPSCs).  Dr. Rao presented his iPSC bank concept for drug development applications in a recent lecture

Leave the Antibodies Alone | Asymmetrex

Leave the Antibodies Alone | Asymmetrex

In their recent comment in Nature arguing that the use of only recombinant antibodies in research would significantly improve reproducibility, Bradbury and Plückthun make the freshman error of becoming so enraptured with the envisioned positive aspects of their ingenuity that they do not consider the many negative ones.  Even if the authors are forgiven for

The Cancer Stem Cell Gamble

Although the cancer stem cell hypothesis for new cancer therapeutics is really no more of a gamble than any other current basis for cancer drug discovery, this article provides a timely, excellent perspective on its historical context and current nuances.  The quoted stem cell scientists criticize with extreme requirements for “proof,” whereas the cancer physicians

Backlash Greets "Bad Luck’ Cancer Study

Backlash Greets “Bad Luck’ Cancer Study

Although sometimes journalists may not get a new science report exactly right in their re-telling of it, they are not responsible for the recent misinformation on cancer causes.  The authors and editors are.  Even more problematic than the many indictments of technical shortcomings in the quality of the data and analyses, the authors misrepresented their

Homologous Adult Stem Cell Therapy

Cancer Patients to Feel Less Hopeful

After reading this recent article in Time Magazine Online, there is no need for cancer patients to feel less hopeful.  The chance induction of cancer due to the chance occurrence of errors when our cells copy DNA for normal cell multiplication has always been true, as well as recognized by some cancer scientists for many

Stem Cell Chromosomes | Biomarkers

Stem Cell Chromosomes | Biomarkers

For Immediate Release Boston, MA (PRWEB) December 04, 2014 The Adult Stem Cell Technology Center, LLC’s New Report on Asymmetric Character of Stem Cell Chromosomes Advances Better Biomarkers for Counting Adult Tissue Stem Cells Today, a new research report from Boston’s Adult Stem Cell Technology Center, LLC, published online in the Nature Publishing Group journal